Original Research Article | OPEN ACCESS

Self-reported health status of a sample of patients receiving in-vitro fertilization treatment

Mudasiru A Bello, Rawlings U Odigie , Anthony W Udezi

Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Benin, PMB 1154, Benin City, 300001, Nigeria.;

For correspondence:-  Rawlings Odigie   Email:  rawlingsod@gmail.com   Tel:  +2347036585490

Published: 31 December 2023

Citation: Bello MA, Odigie RU, Udezi AW. Self-reported health status of a sample of patients receiving in-vitro fertilization treatment. J Sci Pract Pharm 2023; 10(1):514-521 doi: 10.47227/jsppharm.v10i1.4

© 2023 The author(s).
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). This license requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only. .


Purpose: To determine the health status of patients receiving in-vitro fertilization (IVF) treatment and evaluate possible relationships with social demographic factors in comparison to those not receiving infertility treatment.

Methods: The EuroQoL Group-developed EQ5D-5L was used to elicit responses on the five dimensions that make up its health profile; Mobility, Self-Care, Usual Activities, Pain/Discomfort, and Anxiety/Depression.  Respondents scored their perception of how good their health is using a calibrated visual analog scale (VAS) from 0 to 100 with higher values indicating a better-perceived health status. Respondents were randomly selected patients in the waiting area in selected clinics and pharmacies in Abuja, Nigeria. Student's Test and Chi-square were employed for inferential analyses where appropriate. P-values < 0.05 were interpreted as significant.

Results: About 43% of the respondents on IVF treatment reported problems with anxiety and depression compared to 10% of respondents not using IVF (p = 0.0001). They also reported problems with performing usual activities (12%) and pain/discomfort (22%) compared to 3% and 11% respectively for those not on infertility treatment (p < 0.05). Those aged 35-45 years and are currently on IVF treatment reported a significantly lower health status compared to those of the same age range who are not on treatment (p = 0.0001). Study participants on IVF treatment, irrespective of their educational level and marital status, significantly reported a lower health status (p < 0.05). 

Conclusion: Infertility affects quality of life and the domain mostly affected is anxiety and depression. People taking IVF treatment reported a lower health status compared to those not receiving IVF treatment.



Keywords: IVF treatment, quality of life, health status, infertility, EQ5D-5L

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