Original Research Article | OPEN ACCESS

Self-reported health status of a sample of patients receiving in-vitro fertilization treatment

Mudasiru A Bello, Rawlings U Odigie , Anthony W Udezi

Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Benin, PMB 1154, Benin City, 300001, Nigeria.;

For correspondence:-  Rawlings Odigie   Email:  rawlingsod@gmail.com   Tel:  +2347036585490

Published: 31 December 2023

Citation: Bello MA, Odigie RU, Udezi AW. Self-reported health status of a sample of patients receiving in-vitro fertilization treatment. J Sci Pract Pharm 2023; 10(1):514-521 doi: 10.47227/jsppharm.v10i1.4

© 2023 The author(s).
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..


Purpose: To determine the health status of patients receiving in-vitro fertilization (IVF) treatment and evaluate possible relationships with social demographic factors in comparison to those not receiving infertility treatment.

Methods: The EuroQoL Group-developed EQ5D-5L was used to elicit responses on the five dimensions that make up its health profile; Mobility, Self-Care, Usual Activities, Pain/Discomfort, and Anxiety/Depression.  Respondents scored their perception of how good their health is using a calibrated visual analog scale (VAS) from 0 to 100 with higher values indicating a better-perceived health status. Respondents were randomly selected patients in the waiting area in selected clinics and pharmacies in Abuja, Nigeria. Student's Test and Chi-square were employed for inferential analyses where appropriate. P-values < 0.05 were interpreted as significant.

Results: About 43% of the respondents on IVF treatment reported problems with anxiety and depression compared to 10% of respondents not using IVF (p = 0.0001). They also reported problems with performing usual activities (12%) and pain/discomfort (22%) compared to 3% and 11% respectively for those not on infertility treatment (p < 0.05). Those aged 35-45 years and are currently on IVF treatment reported a significantly lower health status compared to those of the same age range who are not on treatment (p = 0.0001). Study participants on IVF treatment, irrespective of their educational level and marital status, significantly reported a lower health status (p < 0.05). 

Conclusion: Infertility affects quality of life and the domain mostly affected is anxiety and depression. People taking IVF treatment reported a lower health status compared to those not receiving IVF treatment.



Keywords: IVF treatment, quality of life, health status, infertility, EQ5D-5L

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